Hello Verena,
Yes, by all means you can handle her during a shed and after. Giving her a
bath would probably be one of the best things you could do for her right now. You can actually give her a few baths a day if you want. Definitely keep her and her skin
hydrated, it helps it come off easier and makes her more comfortable. Try not to pull it off, as to not damage the new scales underneath. If she has any bothersome areas you can use a very soft toothbrush on her. Hope this helps.
Dawn